%0 Journal Article %A Sh Bhandari %A B Bhave %A I Ganguly %A A Baxi %A P Agarwal %B Journal of Reproduction & Infertility %C Tehran, Iran %D 2015 %T Reproductive Outcome of Patients with Asherman’s Syndrome: A SAIMS Experience %J JRI %> https://www.jri.ir/documents/fullpaper/en/660.pdf %U https://www.jri.ir/article/660 %K %P 229-236 %V 16 %N 4 %G English %I Avicenna Research Institute %( Avicenna Research Institute %@ 2251-676X %X

Background: The purpose of the study was to evaluate menstrual and reproductive outcome in patients diagnosed with Asherman’s syndrome on hysteroscopy and to assess the role of hysteroscopic adhesiolysis.
Methods: A prospective study was performed for patients having intrauterine adhesion at a tertiary care teaching hospital, Indore, India for a period of 2 years. Findings at hysteroscopy, details of adhesiolysis, changes in menstrual pattern following adhesiolysis, need for repeat procedure and fertility outcome were prospectively collected. Data was analysed using SPSS software. A p-value of <0.05 was considered significant.
Results: A total of 60 patients with a mean age of 30.1±5.5 years with Asherman’s syndrome were included. In 53.3% of them, no factors like post-partum curettage, uterine surgery or history of tuberculosis could be found in which the present intrauterine adhesions could be attributed to. Hypomenorrhoea was the most common (53.3%) menstrual pattern in patients diagnosed with Asherman’s syndrome. Thirty eight out of 60 (63.33%) required second look hysteroscopy. There was a significant change in endometrial lining and echo pattern after adhesiolysis (p<0.05). 45% of patients started having normal menstrual flow after adhesiolysis which was statistically significant. A total of 16 conceptions and 10 live births were reported in the present cohort. Pregnancy rate was higher in patients having mild Asherman’s syndrome (53.3%) as compared to moderate (26.9%) or severe type (9.5%), (p=0.0049). It was also higher in patients having normal endometrial pattern after adhesiolysis (p=0.0005).
Conclusion: Women who underwent hysteroscopic adhesiolysis showed significant improvement in the menstrual pattern. Pregnancy rates were improved after hysteroscopic adhesiolysis.