TY - JOUR T1 - Chlamydia trachomatis Infection in Pregnant Women T2 - Journal of Reproduction & Infertility JT - Journal of Reproduction & Infertility SP - 121 EP - 129 VL - 10 IS - 2 PY - 2009 SN - 2251-676X L1 - https://www.jri.ir/documents/fullpaper/fa/374.pdf L2 - https://www.jri.ir/article/374 UR - https://www.jri.ir/en/currentissue.aspx?id=39 PB - Avicenna Research Institute AU - Khezerdoust, Soghra AU - Haghollahi, Fedyeh AU - Roostaie, Samin AU - Badami, Naser AU - Naghizadeh, Mohammad Mehdi AU - Jafarabadi, Mina AB - Introduction: Chlamydial infections are the most common sexually transmitted diseases with highest rates of morbidity in different societies. Chlamydia trachomatis is a known causative agent for premature rapture of membranes (PROM), preterm labor, miscarriage, low birth weight and neonatal death, and forms a copious burden of disease in many countries. This study aims to evaluate the prevalence, outcome and risk factors of chlamydial infections.Materials and Methods: This cross-sectional, descriptive-analytical study was done on 1114 pregnant women in their 11th to 32nd week of gestation who attended the hospitals affiliated to Tehran University of Medical Sciences during March 2007 to March 2009. Serum levels of IgG anti-chlamydial antibody were measured by ELIZA method, upon taking a thorough medical history.Results: Positive results for chlamydia IgG were seen in 2.9% of the cases. Chlamydia infection was 2.3 times greater in multiparous women compared to primigravids, (95% CI, 1.1- 4.8). Chorioamnionitis and neonatal death were respectively 4.7 (p=0.027) and 11.6 (p=0.008) times more prevalent in IgG-positive group compared to women without the infection.Conclusion: A relatively low prevalence of chlamydial infection was observed in the studied population. Further studies in different groups of pregnant women, especially in cases attending private health sector, are recommended to be done in order to justify the necessity of routine Chlamydia screening in pregnancy and the obligation for preventive care measurements in Iranian pregnant women. CY - Tehran, Iran KW - Chlamydia trachomatis KW - Complications KW - Neonatal death KW - Pregnancy KW - Serology KW - Sexually transmitted infection LA - Persian