en
1726-7536
1735-8507
69
2139
288
gregorian
2014
10
14
15
4
online
1
fulltext
en
25473626
Accurate Diagnosis as a Prognostic Factor in Intrauterine Insemination Treatment of Infertile Saudi Patients
<p>Background: The study meant to define the prognostic factors that help in prescribing intrauterine insemination (IUI) for infertility treatment which remains an area of continuous improvements. Methods: The diagnostic indications of a cohort of IUI-treated patients and their corresponding pregnancy rates (PRs) were randomly and prospectively studied among Saudi cohort of 303 patients for a period of 20 months. The indications of IUI cases were statistically analyzed for those eligible patients over a period of twenty months (January 2010 till August 2011), and the PR that corresponded to each group was investigated as well. P-value less than 0.05 was considered significant. Results: The highest PR, 18.87%, of the polycystic ovarian syndrome (PCOS)-only diagnosed patients, was significantly higher than the average PR of all other indications combined, 7.22%, (p=0.011, compared to all other groups combined). The second highest PR, 14.0%, of the tubal factor (TF)-only indication, was double the PR average of all other indications combined, though it did not reach significance. However, PCOS and TF accompanied by other indications caused the PR to drop to 5.88% and 5.56 %, respectively. However, a group of some hormonal-imbalance based indications had the least PR (0.0% to 2.70%). Those indications were elevated serum FSH, hyperprolactinemia, hypogonadotrophy, hypothyroidism and endometriosis. The rest of the indications had an average PR (8.33% to 11.11%). Conclusion: There is a reasonable chance of conception after IUI treatment for female factor infertility except in cases with sever hormonal imbalance. The PCOS cases having the best success chances.</p>
Diagnosis, Endometriosis, Intra uterine insemination, IUI, Male factor, PCOS, Pregnancy rate, Tubal Factor
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https://www.jri.ir/article/561
https://www.jri.ir/documents/fullpaper/en/561.pdf
AhmedIsaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabiaisaahmed@hotmail.com1252
BasimAbu-RafeaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1249
SalehAlasiriDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1250
JoharaAl-MutawaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1306
SalehBinsalehUrology Division, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia1344
SameeraAl-SaifDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1307
AishaAl-SaqerDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1308