J Reprod Infert arij001 Journal of Reproduction & Infertility 2228-5482 2251-676X Avicenna Research Institute jri660 Reproductive Outcome of Patients with Asherman’s Syndrome: A SAIMS Experience BhandariShilpaDepartment of Reproductive Medicine, Sri Aurobindo Medical College and PG Institute, Indore, IndiaBhavePriyaDepartment of Reproductive Medicine, Sri Aurobindo Medical College and PG Institute, Indore, IndiaGangulyIshitaDepartment of Reproductive Medicine, Sri Aurobindo Medical College and PG Institute, Indore, IndiaBaxiAshaDepartment of Reproductive Medicine, Sri Aurobindo Medical College and PG Institute, Indore, IndiaAgarwalPallaviDepartment of Reproductive Medicine, Sri Aurobindo Medical College and PG Institute, Indore, India 16 4 229 236 15 12 2014 19 4 2015

<p>Background: The purpose of the study was to evaluate menstrual and reproductive outcome in patients diagnosed with Asherman&rsquo;s syndrome on hysteroscopy and to assess the role of hysteroscopic adhesiolysis.<br /> Methods: A prospective study was performed for patients having intrauterine adhesion at a tertiary care teaching hospital, Indore, India for a period of 2 years. Findings at hysteroscopy, details of adhesiolysis, changes in menstrual pattern following adhesiolysis, need for repeat procedure and fertility outcome were prospectively collected. Data was analysed using SPSS software. A p-value of &lt;0.05 was considered significant.<br /> Results: A total of 60 patients with a mean age of 30.1&plusmn;5.5 years with Asherman&rsquo;s syndrome were included. In 53.3% of them, no factors like post-partum curettage, uterine surgery or history of tuberculosis could be found in which the present intrauterine adhesions could be attributed to. Hypomenorrhoea was the most common (53.3%) menstrual pattern in patients diagnosed with Asherman&rsquo;s syndrome. Thirty eight out of 60 (63.33%) required second look hysteroscopy. There was a significant change in endometrial lining and echo pattern after adhesiolysis (p&lt;0.05). 45% of patients started having normal menstrual flow after adhesiolysis which was statistically significant. A total of 16 conceptions and 10 live births were reported in the present cohort. Pregnancy rate was higher in patients having mild Asherman&rsquo;s syndrome (53.3%) as compared to moderate (26.9%) or severe type (9.5%), (p=0.0049). It was also higher in patients having normal endometrial pattern after adhesiolysis (p=0.0005).<br /> Conclusion: Women who underwent hysteroscopic adhesiolysis showed significant improvement in the menstrual pattern. Pregnancy rates were improved after hysteroscopic adhesiolysis.</p>