TY - JOUR T1 - Evaluation of L-Carnitine Potential in Improvement of Male Fertility T2 - Journal of Reproduction & Infertility JT - Journal of Reproduction & Infertility SP - 069 EP - 85 VL - 24 IS - 2 PY - 2023 SN - 2251-676X L1 - https://www.jri.ir/documents/fullpaper/en/140181.pdf L2 - https://www.jri.ir/article/140181 UR - https://www.jri.ir/en/currentissue.aspx?id=95 PB - Avicenna Research Institute AU - Kooshesh, Leila AU - Nateghian, Zohre AU - Aliabadi, Elham AB -

L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.

CY - Tehran, Iran LA - English