en 37547570 <p>L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.</p> Busulfan, L-carnitine, Male fertility, Radiation, Sperm cryopreservation 069 85 https://www.jri.ir/article/140181 https://www.jri.ir/documents/fullpaper/en/140181.pdf LeilaKoosheshDepartment of Genetics, Fars Academic Center for Education, Culture and Research, ACECR, Shiraz, Iran122503ZohreNateghianIslamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, Iran122504ElhamAliabadiDepartment of Anatomy, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, IranElhamAliabadialiabade@sums.ac.ir1117