en 40352445 <p>Background: The objective of this study was to evaluate the model of spiritual health in relation to psychological distress among infertile women, with perceived social support as a mediator.<br /> Method: In this study, structural equation modeling (SEM) was employed. The study population included all infertile women in Shiraz from which a sample of 250 individuals was selected using a targeted sampling method. The research data were collected by Spiritual Health questionnaire developed by Iranian Academy of Medical Sciences; Depression, Anxiety, and Stress Scale 21 (DASS-21); and Multidimensional Scale of Perceived Social Support (MSPSS). Data analysis was performed using SPSS and AMOS software.<br /> Results: The results demonstrate that the direct impact of spiritual health on psychological distress and perceived social support was statistically significant. Furthermore, a significant indirect effect of spiritual health on psychological distress was identified through perceived social support.<br /> Conclusion: According to the findings of this study, it may be beneficial to address aspects of spiritual health and social support to alleviate psychological distress among infertile women.</p> Infertility, Perceived social support, Psychological distress, Spiritual health 290 298 https://www.jri.ir/article/140246 https://www.jri.ir/documents/fullpaper/en/140246.pdf FarideEnsafdaranResearch Center of Quran, Hadith and Medicine, Shiraz University of Medical Sciences, Shiraz, Iranf.ensafdaran@gmail.com122764MahmoudNejabatResearch Center of Quran, Hadith and Medicine, Shiraz University of Medical Sciences, Shiraz, Iran122765SoudabehSabetianDepartment of Biostatistics, Infertility Research Center, Shiraz University of Medical Sciences, Shiraz, Iranسودابهثابتیان806BahiaNamavar JahromiDepartment of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran72026FatemehHemmatiFatemieh Institute of Higher Education, Shiraz, Iran122767