en 32500018 <p>Background: The objective of this case presentation was describing a live birth in an advanced-age woman with an extremely enlarged uterus, an ovary with blocked fallopian tubes, hypothyroidism and generalized anxiety disorder caused by childbirth following intracytoplasmic sperm injection/embryo transfer (ICSI-ET) with autologous oocytes.&nbsp;<br /> Case Presentation: A 47-year-old patient with an enlarged uterus due to recurrent multiple fibroids following myomectomy was referred to clinical laboratory with a high level of desire to follow the prescribed recommendations and approaches to retrieve her fertility. The patient underwent two cycles of oocyte retrieval and two rounds of frozen-thawed embryo transfer. To achieve a successful pregnancy after oocyte retrieval (birth weight of 3300 <em>g</em> at 38 weeks of gestation), a frozen/thawed embryo in the second cycle of ET was transferred.<br /> Conclusion: Usage of efficient planning and management of ICSI treatments in patient with autologous oocytes and concurrent disorders, can be used as a new approach to cure the affected individuals.</p> Advanced maternal age, Autologous oocytes, Embryo transfer, Intracytoplasmic sperm injection, Live birth 146 151 https://www.jri.ir/article/60081 https://www.jri.ir/documents/fullpaper/en/60081.pdf FaranakAghazFertility and Infertility Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran61942ZahraMokariDepartment of Social Sciences, Razi University, Kermanshah, Iran62053MitraBakhtiariInfertility Research and Treatment Center, Motazedi Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iranmiana512000@yahoo.com31882