en 26962481 <p>Background: There is a growing concern about the high prevalence of vitamin D deficiency and its relationship with variety of diseases worldwide. The objective of this study was to determine the prevalence of vitamin D deficiency and its relationship with pregnancy adverse effects in Yazd.<br /> Methods: This was a cross sectional study conducted among 200 nulliparous women from October 2013 to April 2014. Data containing socio-demographic and personal details, vitamin D level, pregnancy complications and growth situation of newborns were collected and analyzed using Mann-Whitney, Kruskal-Wallis and Pearson&rsquo;s correlation coefficient by SPSS. p&lt;0.05 was considered statistically significant.<br /> Results: The mean serum 1, 25 (OH)₂D₃ concentration was 20.3&plusmn;10.8<em> &micro;g/l</em>. Totally, 78% of the women had less than sufficient levels. Mean of vitamin D was significantly higher in natural or elective cesarean in comparison with abortion and emergency cesarean (p=0.040). Risk of abortion was 3.1(1.39-6.8) and higher in severely deficient group in comparison to women with vitamin D deficiency (p=0.017) and mean of vitamin D group was significantly lower in women who had oligohydramnios or polyhydramnios complication (p=0.045).<br /> Conclusion: The study findings revealed that vitamin D deficiency is prevalent in pregnant women and it is significantly associated with elevated risk for abortion, and oligohydramnios or polyhydramnios. Probably, a targeted screening strategy can be suggested to detect and treat women at high risk of vitamin D deficiency in early pregnancy as a simple way to reduce the risk of these adverse pregnancy outcomes in Yazd.</p> Pregnancy complications, Vitamin D deficiency, Women 34 39 https://www.jri.ir/article/633 https://www.jri.ir/documents/fullpaper/en/633.pdf AzarPirdehghanCommunity and Preventive Medicine Department, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iranpirdehghan93@gmail.com1445MahmoodVakiliCommunity and Preventive Medicine Department, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1446ReyhaneDehghanHealth Research Center Community and Preventive Medicine Department, School of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1447FatemehZare Gynecology Department, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1448