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25469325
Methodological Considerations in Studying Sexual Behaviors of Young People in Iran
171
173
https://www.jri.ir/article/605
https://www.jri.ir/documents/fullpaper/en/605.pdf
FaridehKhalajabadi-FarahaniDepartment of Population, Health and Family Planning, National Institute for Population Research, Tehran, Iranfaridehfarahani2@gmail.com1388
en
25473625
Recurrent Implantation Failure: The Role of the Endometrium
<p>The success rate of reproductive treatment methods depends on many different factors. The most important and discussed ones in the literature are maternal age, the causes of infertility, the ovarian response to stimulation, the influence of the male factor and sperm quality, embryo quality and the various uterine pathologies. Some couples fail repeatedly after transferring good quality embryos without any obvious reason and this becomes a major continuing problem after IVF/ICSI procedures. It can be speculated that in these couples, insufficiency of the endometrium might be a possible reason for implantation failure. This review article summarized current literature describing the consecutive endomertial procedures involved in successful embryo implantation. It is believed that efforts to align criteria for definition of recurrent implantation failure (RIF) and attempts to classify different RIF types would develop guidelines for treatment procedures which would result in an increase in patients’ opportunities to conceive.</p>
Decidua, Embryo implantation, Endometrium, <i>In Vitro</i> fertilization, Reproductive physiological phenomena
173
184
https://www.jri.ir/article/597
https://www.jri.ir/documents/fullpaper/en/597.pdf
TanyaTimevaSpecialized Ob/Gyn Hospital for Active Treatment, Sofia, Bulgariattimeva@yahoo.com1310
AtanasShterevSpecialized Ob/Gyn Hospital for Active Treatment, Sofia, Bulgaria1311
StanimirKyurkchievInstitute of Reproductive Health, Sofia, Bulgaria1312
en
25473626
Accurate Diagnosis as a Prognostic Factor in Intrauterine Insemination Treatment of Infertile Saudi Patients
<p>Background: The study meant to define the prognostic factors that help in prescribing intrauterine insemination (IUI) for infertility treatment which remains an area of continuous improvements. Methods: The diagnostic indications of a cohort of IUI-treated patients and their corresponding pregnancy rates (PRs) were randomly and prospectively studied among Saudi cohort of 303 patients for a period of 20 months. The indications of IUI cases were statistically analyzed for those eligible patients over a period of twenty months (January 2010 till August 2011), and the PR that corresponded to each group was investigated as well. P-value less than 0.05 was considered significant. Results: The highest PR, 18.87%, of the polycystic ovarian syndrome (PCOS)-only diagnosed patients, was significantly higher than the average PR of all other indications combined, 7.22%, (p=0.011, compared to all other groups combined). The second highest PR, 14.0%, of the tubal factor (TF)-only indication, was double the PR average of all other indications combined, though it did not reach significance. However, PCOS and TF accompanied by other indications caused the PR to drop to 5.88% and 5.56 %, respectively. However, a group of some hormonal-imbalance based indications had the least PR (0.0% to 2.70%). Those indications were elevated serum FSH, hyperprolactinemia, hypogonadotrophy, hypothyroidism and endometriosis. The rest of the indications had an average PR (8.33% to 11.11%). Conclusion: There is a reasonable chance of conception after IUI treatment for female factor infertility except in cases with sever hormonal imbalance. The PCOS cases having the best success chances.</p>
Diagnosis, Endometriosis, Intra uterine insemination, IUI, Male factor, PCOS, Pregnancy rate, Tubal Factor
184
190
https://www.jri.ir/article/561
https://www.jri.ir/documents/fullpaper/en/561.pdf
AhmedIsaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabiaisaahmed@hotmail.com1252
BasimAbu-RafeaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1249
SalehAlasiriDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1250
JoharaAl-MutawaDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1306
SalehBinsalehUrology Division, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia1344
SameeraAl-SaifDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1307
AishaAl-SaqerDepartment of Obstetrics and Gynecology, College of Medicine, King Saud University, Riyadh, Saudi Arabia1308
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25473627
Comparison of Elaeagnus angustifolia Extract and Sildenafil Citrate on Female Orgasmic Disorders: A Randomized Clinical Trial
<p>Background: Orgasmic disorder can create a feeling of deprivation and failure and provide mental problems, incompatibility and marital discord. This study aimed to compare the effects of Elaeagnus angustifolia flower extract and sildenafil citrate on female orgasmic disorder in women in 2013. Methods: In this randomized clinical trial, 125 women between 18-40 years old who suffered from orgasmic disorder were divided into three E. angustifolia, sildenafil citrate and control groups. The data were gathered using Female Sexual Function Index and through measurement of TSH and prolactin. The first intervention group had to consume 4.5 gr E. angustifolia extract in two divided doses for 35 days and the second one had to use 50 mg sildenafil citrate tablets for 4 weeks one hour before their sexual relationship. However, the control group had to consume the placebo. The data were analyzed using paired t-test, one-way ANOVA, and Bonferroni post-hoc test and p<0.05 was considered significant. Results: The frequency of orgasmic disorder before the intervention was 41.5%, 40.5%, and 57.1% in E. angustifolia, sildenafil citrate, and control groups, respectively (p=0.23). However, these measures were respectively 29.3%, 16.7%, and 50% after the intervention (p=0.004). A significant difference between the two groups regarding sexual satisfaction after the intervention (p=0.003) compared to the beginning of the study (p=0.356). Besides, the highest reduction of changes after the intervention (58.82%) was observed in the sildenafil citrate group. Conclusion: Both E. angustifolia extract and sildenafil citrate were effective in reduction of the frequency of orgasmic disorder in women.</p>
Elaeagnus angustifolia, Orgasmic disorder, Sildenafil citrate
190
199
https://www.jri.ir/article/599
https://www.jri.ir/documents/fullpaper/en/599.pdf
MarziehAkbarzadehCommunity Based Psychiatric Care Research Center, Department of Midwifery, Fatemeh (P.B.U.H) School of Nursing and Midwifery, Shiraz University of Medical Sciences,, Shiraz, Iranakbarzadm@sums.ac.ir1317
SanazZeinalzadehDepartment of Midwifery, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran1318
JalehZolghadriDepartment of Obstetrics and Gynecology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran1319
AbdolaliMohagheghzadehDepartment of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran1320
PouyaFaridiDepartment of Traditional Pharmacy, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran1321
MehrabSayadiDepartment of Bio-statistics, Shiraz University of Medical Sciences, Shiraz, Iran1322
en
25473628
Vasopressin Effect on Operation Time and Frequency of Electrocauterization during Laparoscopic Stripping of Ovarian Endometriomas: A Randomized Controlled Clinical Trial
<p>Background: The purpose of this study was to assess the vasopressin effect on operation time and the need for electrocauterization frequency and ovarian reserve during laparoscopic stripping of ovarian endometriomas. Methods: This was a randomized prospective clinical trial, in which twenty patients between 18-35 years with unilateral endometriomas were randomly divided in two groups of cases and controls. Laparoscopic cystectomy was performed by hydrodissection and stripping method in both groups with diluted vasopressin injected in cases, in comparison to only saline injection in controls. Ovarian hemostasis was achieved by bipolar electrocoagulation. The operation time and frequency of electrocoagulation were compared between two groups. The ovarian reserve was determined by ultrasound examination and laboratory assessment one month before and two months after surgery in two groups. Non parametric data was analyzed by Mann-Whitney test. The p-value less than 0.05 was considered statistically significant. Results: The operation time was less in cases than control group, but the difference was not statistically significant (p=0.065). The frequency of electrocoagulation for hemostasis was less in cases than controls but this difference was not statistically significant (p=0.132). The antral follicle count decreased in both groups two months later, while no significant difference was found between two groups. Conclusion: This study shows that diluted vasopressin decreases operation time and electrocauterization frequency during laparoscopic stripping of ovarian endometriomas; however, the difference between case and control group is not statistically significant.</p>
Electrocoagulation, Endometriosis, Laparoscopy, Vasopressin
199
205
https://www.jri.ir/article/606
https://www.jri.ir/documents/fullpaper/en/606.pdf
MarziehGhafarnejadDepartment of Obstetrics and Gynecology, Women Hospital, Tehran University of Medical Sciences, Tehran, Iranghafarin2@yahoo.com1345
MinaAkramiDepartment of Obstetrics and Gynecology, Women Hospital, Tehran University of Medical Sciences, Tehran, Iran1346
FatemehDavari-TanhaDepartment of Obstetrics and Gynecology, Women Hospital, Tehran University of Medical Sciences, Tehran, Iran1347
KhadijehAdabiDepartment of Obstetrics and Gynecology, Women Hospital, Tehran University of Medical Sciences, Tehran, Iran1348
SepidehNekuieWomen Hospital, Tehran University of Medical Sciences, Tehran, Iran1349
en
25473629
Effect of Metformin and Flutamide on Anthropometric Indices and Laboratory Tests in Obese/Overweight PCOS Women under Hypocaloric Diet
<p>Background: This study was designed to investigate the effect of metformin and flutamide alone or in combination with anthropometric indices and laboratory tests of obese/overweight PCOS women under hypocaloric diet. Methods: This single blind clinical trial was performed on 120 PCOS women. At the beginning, hypocaloric diet was recommended for the patients. After one month while they were on the diet, the patients were randomly divided in 4 groups; metformin (500 mg, 3/day), flutamide (250 mg, 2/day), combined, metformin (500 mg, 3/day) with flutamide (250 mg, 2/day) and finally placebo group. The patients were treated for 6 months. Anthropometric indices and laboratory tests (fasting and glucose-stimulated insulin levels, lipid profile and androgens) were measured. A one-way ANOVA (Post Hoc) and paired t-test were performed to analyze data. A p≤0.05 was considered statistically significant. Results: After treatment, reduction in weight, BMI, hip circumference was significantly greater in the metformin group in comparison to other groups (p<0.05). In addition, the fasting insulin was significantly greater in metformin group and flutamide group in comparison to metformin+flutamide and placebo groups after treatment (p<0.05). Within groups, insulin level showed significant changes (before and after treatment) in metformin+flutamide group and LDL reduction was significant in flutamide group before and after treatment. Post hoc tukey and two-tailed with p≤0.05 were used to define statistical significance. Conclusion: Using combination of metformin and flutamide improves anthropometric indices and laboratory tests in obese/overweight PCOS women under hypocaloric diet.</p>
Body weight, Flutamide, Metformin, Polycystic ovary syndrome
205
214
https://www.jri.ir/article/601
https://www.jri.ir/documents/fullpaper/en/601.pdf
ManiaAmiriFatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran1328
MasoumehGolsorkhtabar-AmiriFatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran1326
SedighehEsmaeilzadehFatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iransesmael@yahoo.com262
FaezeGhofraniFatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran1331
AliBijaniNon-Communicable Pediatric Disease Research Center, Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, Iran1329
LeilaGhorbaniObstetrics and Gynecology Department, Babol University of Medical Sciences, Babol, Iran1327
MoloudAgajani DelavarFatemezahra Infertility and Reproductive Health Research Center, Babol University of Medical Sciences, Babol, Iran1330
en
25473630
Relationship between Dietary Fat Intake, Its Major Food Sources and Assisted Reproduction Parameters
<p>Background: High dietary fat consumption may alter oocyte development and embryonic development. This prospective study was conducted to determine the relation between dietary fat consumption level, its food sources and the assisted reproduction parameters. Methods: A prospective study was conducted on 240 infertile women. In assisted reproduction treatment cycle, fat consumption and major food sources over the previous three months were identified. The number of retrieved oocytes, metaphase ΙΙ stage oocytes numbers, fertilization rate, embryo quality and clinical pregnancy rate were also determined. The data were analyzed using multiple regression, binary logistic regression, chi-square and t-test. The p-value of less than 0.05 was considered significant. Results: Total fat intake adjusted for age, body mass index, physical activity and etiology of infertility was positively associated with the number of retrieved oocytes and inversely associated with the high embryo quality rate. An inverse association was observed between sausage and turkey ham intake and the number of retrieved oocytes. Also, oil intake level had an inverse association with good cleavage rate. Conclusion: The results revealed that higher levels of fat consumption tend to increase the number of retrieved oocytes and were adversely related to embryonic development. Among food sources of fat, vegetable oil, sausage and turkey ham intake may adversely affect assisted reproduction parameters.</p>
Assisted reproduction, Dietary fats, Embryo quality, Pregnancy rate
214
222
https://www.jri.ir/article/559
https://www.jri.ir/documents/fullpaper/en/559.pdf
AshrafKazemiReproductive Health Department, Nursing and Midwifery Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranKazemi@nm.mui.ac.ir1309
FatemehRamezanzadehReproductive Health Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iranفاطمهرمضان زاده723
Mohammad HosseinNasr-EsfahaniReproductive Biomedicine Center, Royan Institute for Animal Biotechnology, ACECR, Department of Reproduction and Development, Isfahan, Iran168
en
25473631
Zoroastrians Support Oocyte and Embryo Donation Program for Infertile Couples
<p>Background: The main goal was to evaluate the attitudes and knowledge of Zoroastrians living in Iran towards oocyte donation (OD) and embryo donation (ED) program. Methods: This cross sectional study consisted of 318 Zoroastrians (n=175 for OD and n=143 for ED) of both sexes. The questionnaire form comprised two parts of general demographic characteristics of the participants and twenty multiple-choice questions about attitude and knowledge of participants towards OD and ED. For statistical analysis, the chi-square test was applied for comparison of data generated from ED and OD groups. Results: Majority of the participants supported OD (69.7%) and ED (71.3%) for infertile patients. In addition, 40% and 42% preferred donation program (OD and ED, respectively), compared to adoption. About 60% of the respondents believed that the donors have no right to find the child and claim it as their own. In addition, more than half of the respondents thought that the recipients of oocyte/embryo should never know the name and address of the donors. More than half of the participants did not know whether their religion accepts donation program or not. Approximately, 80% of respondents supported psychological counseling for both donors and recipients. Moreover, about 56% of the participants necessitated the advertisement on OD/ED program in the mass media. Conclusion: Our preliminary data showed that Zoroastrians supported both OD and ED program equally for infertile couples.</p>
Embryo donation, Iran, Oocyte donation, Zoroastrians
222
229
https://www.jri.ir/article/600
https://www.jri.ir/documents/fullpaper/en/600.pdf
ImanHalvaeiResearch and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, IranImanHalvaei1019
Mohammad AliKhaliliResearch and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iranمحمد عليخليليkhalili59@hotmail.com84
SaeedGhasemi-EsmailabadResearch and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1323
AliNabiResearch and Clinical Center for Infertility, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1324
FarimahShamsiCollege of Health, Department of Biostatistics and Epidemiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran1325
en
25469326
Demons-Meigs Pseudosyndrome Mimicking the Symptoms of Pregnancy: A Case Report
<p>Background: The Demons-Meigs syndrome should usually be evoked in case of presence of a typical triad: abdominopelvic mass, ascites and hydrothorax. Its diagnosis appears crucial to prevent the realization of unnecessary surgical procedures. Case Presentation: A 32-year-old woman presented in April 2012 to the emergency department of our maternity unit (General Hospital, Thiers, France) with an abdominal distension mimicking the symptoms of a pregnancy at term. Physical examination revealed a voluminous painful abdominopelvic mass, extended from the pelvis to the upper abdomen with a large right pleural effusion. Ultrasound and computed tomography showed it was a tumor measuring more than 300 mm in diameter with a right hydrothorax. Serum CA-125 level was 289 U/ml. Cytologic analysis of the pleural effusion didn’t show any malignant cells. In this study, Demons-Meigs syndrome was recognized. A laparoscopico-laparotomic management permitted an aspiration of 23 liters of a brownish liquid and an unilateral adnexectomy after pleural paracentesis was performed. Frozen section demonstrated benign mucinous cystadenoma. The final histologic findings objectified intracystic intestinal type ovarian mucinous borderline tumor. After multidisciplinary consultation, the patient was re-operated one month later. The exploration didn’t reveal any suspected lesions and appendectomy and omentectomy were performed. The postoperative course was uneventful. Serum CA-125 level was normal at the time of the reoperation and 24 months after the initial surgery. Conclusion: The preoperative recognition of a Demons-Meigs syndrome or a Demons’ pseudosyndrome is essential to avoid useless surgical procedures.</p>
Abdominal mass, Demons-Meigs syndrome, Hydrothorax, Meigs, Ovarian benign tumor
229
233
https://www.jri.ir/article/603
https://www.jri.ir/documents/fullpaper/en/603.pdf
ErdoganNohuzDepartment of Surgery, General Hospital of Thiers, Thiers, Franceenohuz@yahoo.fr1334
MaherAlaboudDepartment of Obstetrics and Gynecology, General Hospital of Thiers, Thiers, France1335
BilalEl-DrayiDepartment of Anesthesiology and Critical Care Medicine, General Hospital of Thiers, Thiers, France1336
StefanoTamburroDepartment of Obstetrics and Gynecology, General Hospital of Grosseto, Grosseto, Italy1337
SaidKachkachDepartment of Radiology, General Hospital of Thiers, Thiers, France1338
JanosVargaDepartment of Surgery, General Hospital of Thiers, Thiers, France1339
en
25469327
Successful Pregnancy Following Myomectomy for Giant Uterine Fibroid in an Infertile Woman
<p>Abstract Background: Giant uterine fibroid is a rare tumor of the uterus, usually symptomatic requiring surgical intervention. Uterine fibroid is generally common among black women. Case Presentation: In this study, a case of 31 year old nullipara was reported who presented to the Gynaecology unit of Enugu State University Teaching Hospital (ESUTH), Nigeria with a history of progressive abdominal swelling of 8 years duration, six years duration of infertility and weight loss and dyspnoea on exertion. Physical examination and transabdominal ultrasound revealed a huge abdominopelvic mass. She had myomectomy. She had a histologically confirmed giant uterine fibroid that weighed 16.8 kg. She subsequently achieved a live birth. Conclusion: Giant uterine fibroids are relatively rare. It poses great challenges in its management. The surgical option of management should consider the fertility preservation and aspiration of couples especially in developing countries.</p>
Giant leiomyoma, Giant uterine fibroid, Infertility, Myomectomy, Nigeria
233
237
https://www.jri.ir/article/604
https://www.jri.ir/documents/fullpaper/en/604.pdf
EuzebusEzugwuDepartment of Obstetrics and Gynaecology, University of Nigeria, Teaching Hospital, Enugu State, Nigeriaezugwueuzebus@yahoo.com1340
ChukwuemekaIyokeDepartment of Obstetrics and Gynaecology, University of Nigeria, Teaching Hospital, Enugu State, Nigeria1341
FrankEzugwuDepartment of Obstetrics and Gynaecology, Enugu State University, Teaching Hospital, Enugu State, Nigeria1342
GeorgeUgwuDepartment of Obstetrics and Gynaecology, University of Nigeria, Teaching Hospital, Enugu State, Nigeria1343