en
1726-7536
1735-8507
69
2139
288
gregorian
2019
3
18
20
2
online
1
fulltext
en
31058049
Metabolomics of Male Infertility: A New Tool for Diagnostic Tests
<p>Infertility is a major health issue worldwide. Males and females contribute equally to this problem. Diagnostic semen analysis fails to identify 50% of male infertility disorders. In this regard, metabolomics as a new field of omics has been suggested to have the potential of solving and diagnosis of the male infertility problems. Metabolome has a history of around 20 years. However, there are only limited metabolomics studies carried out regarding male infertility. In this review, the current metabolomics researches that have been done in infertile men were reviewed. Based on our own results, using human seminal plasma for metabolomics studies is highly recommended to find potential biomarkers and developing diagnosis tests for detection of main deficiencies in infertile men.</p>
Biomarkers, Human seminal plasma, Male infertility, Metabolomics
064
70
https://www.jri.ir/article/50050
https://www.jri.ir/documents/fullpaper/en/50050.pdf
BaharehMehrparavarReproductive Biotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran51905
ArashMinai-TehraniNanobiotechnology Research Center, Avicenna Research Institute, ACECR, Tehran, Iran1389
BabakArjmandIntegrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iran11819
KambizGilanyIntegrative Oncology Department, Breast Cancer Research Center, Motamed Cancer Institute, ACECR, Tehran, Iranكامبيزگيلانيk.gilany@avicenna.ac.ir932