J Reprod Infert arij001 Journal of Reproduction & Infertility 2228-5482 2251-676X Avicenna Research Institute jri140181 Evaluation of L-Carnitine Potential in Improvement of Male Fertility KoosheshLeilaDepartment of Genetics, Fars Academic Center for Education, Culture and Research, ACECR, Shiraz, IranNateghianZohreIslamic Azad University of Isfahan (Khorasgan) Branch, Isfahan, IranAliabadiElhamDepartment of Anatomy, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran 24 2 069 85 15 10 2022 29 12 2022

<p>L-carnitine, through its antioxidant potential, plays a significant role in reducing ROS production in male genital tract; therefore, fundamental improvements in spermatogenesis process and sperm structural and functional parameters in seminal plasma can be observed by treatment with L-carnitine. A literature search was performed using PubMed (including Medline) from the database earliest inception to 2021. Eligibility criteria included studies on protective effects of L-carnitine against damages to the male reproductive system. Based on the findings of the current study, L-carnitine has an effective potential to protect testis and improve conventional and functional sperm parameters against ROS-induced damages by sperm cryopreservation, busulfan treatment, and radiation.</p>