JRI 

Farnaz Sohrabvand Corresponding Author
- Vali-e- Asar Reproductive Health Research Center,Tehran Medical Sciences University, Tehran, Iran
Mamak Shariat
- Vali-e- Asar Reproductive Health Research Center,Tehran Medical Sciences University, Tehran, Iran
Fedyeh Haghollahi
- Vali-e- Asar Reproductive Health Research Center,Tehran Medical Sciences University, Tehran, Iran
Soghra Khezerdoust
- Vali-e- Asar Reproductive Health Research Center,Tehran Medical Sciences University, Tehran, Iran
Abbas Rahimi Foroushani
- Epidemiology Department, Faculty of Publi Health, Tehran Medical Sciences University, Tehran, Iran
Leili Nazemi
- Human Nutrition and Biochemistry Department, Faculty of Public Health, Tehran Medical Sciences University, Tehran, Iran
Maryam Chammari
- Human Nutrition and Biochemistry Department, Faculty of Public Health, Tehran Medical Sciences University, Tehran, Iran

Received: 4/1/2006 Accepted: 4/1/2006 - Publisher : Avicenna Research Institute

Related Articles

 

Other Format

 


Abstract

Introduction: Leg cramps are common painful spasms especially in the lower extremities during pregnancy. The purpose of this study was to find a suitable alternative in the treatment of the disease. Materials & Methods: 217 patients reported leg cramps with different degrees and frequencies among 401 pregnant women in the second half of their pregnancies who visited the Prenatal Clinic of Imam Khomeini Hospital from July to December 2002. After preliminary evaluations for ruling out electrolyte imbalances or insufficient supply of dietary micronutrients, patients were randomly allocated into supplemental therapy (Calcium, magnesium or vitamin B intake for 2 weeks) and control groups. The groups were compared after 4 weeks according to their complete relief from leg cramps. The clinical findings and the data collected from the patients were analyzed by chi-square and t-student tests and a logistic regression model using the SPSS (V.10) software. Results: There was a significant improvement in patients receiving vitamin B with 71% complete and 19% relative relief from leg cramps, compared to 9% complete relief in the control group- 29% and 52% in the groups receiving magnesium and calcium respectively (p<0.0001 ). conclusion: although the high prevalence of leg cramps (55%) in the patients was not necessary-ly related to dietary habits, but it seemed that supplementing symptomatic patients with vitamin b could be beneficial.< pan>


Keywords: Leg cramps, Vitamin B1, Vitamin B6, Pregnancy, Calcium, Magnesium, Supplemental therapy


To cite this article:


References

  1. Schwellnus M.P. Skeletal muscle cramps during exer- cise: The physician & Sport medicine.1999;27:12-13.
  2. Duke J.A. Total health for women: Muscle cramp. 2000;Rodale book.
  3. Herbal remedies, USA site. Muscle cramps, muscle spasm, leg cramps, feet cramps.2001.
  4. Valbo A., Bohmer T. Leg cramps in pregnancy How common are they? Tidsskr Nor laegeform.1999;119 (11):1589-90.
  5. Gary F. Cunningham F.C. Medical & surgical compli-cations in pregnancy. Williams Obstetrics.21st Edition, Mc Graw hill.2001;p:1141.
  6. Cunningham F.C. Renal & Urinary Tract disorders: Williams Obstetrics. 21st Edition, MC Graw Hill.2001; p:1251.
  7. Young G.L., Jewell D. Interventions for leg cramps in pregnancy. Cochrane Database Syst Nov.2002;(2):CD 000121.
  8. Avsar A.F., Ozmen S., Soylemez F. Vit ?1 & B6 substitution in pregnancy for leg cramps. Am J Obsted Gynecol.1996;125(1):233-4.
  9. Dahle L.O., Berg G., Hammar M., Hurtig M., Larsson L., et al. The effect of oral Magnesium substation on pregnancy, Induced leg cramps. Am J Obstet Gynecol. 1995;173 (1):175-180.
  10. Young G.C., Jewell D. Intervention for leg cramps in pregnancy. Cochrane Database Syst Rev.2000;(2): CD 000121.
  11. Hammer M., Larsson L. Calcium treatment of leg cramps in pregnancy effect on clinical symptoms and total serum and ionized serum calcium concentration. Acta Obstet Gynecol Scand.1981;60(4):345-7.
  12. Frussor A., Zarate M., Augustovki M. Magnesium for the treatment of nocturnal leg cramps: a cross over randomized trial. J Fam Pract.1999;48(11):868-71.
  13. Surgery B.C., Sowerbery T. Interventions for leg cramps in pregnancy. Cochrane Data Base Syst Rev. 2002;(1):CD000121.

COPE
SID
NLM
AJMB
IJBMLE
IJBMLE

Home | About Us | Current Issue | Past Issues | Submit a Manuscript | Instructions for Authors | Subscribe | Search | Contact Us

"Journal of Reproduction & Infertility" is owned, published, and managed by Avicenna Research Institute .
Creative Commons License

This work is licensed under a Creative Commons Attribution –NonCommercial 4.0 International License which allows users to read, copy, distribute and make derivative works for non-commercial purposes from the material, as long as the author of the original work is cited properly.

Journal of Reproductoin and Infertility (JRI) is a member of COMMITTEE ON PUBLICATION ETHICS . Verify here .

©2024 - eISSN : 2251-676X, ISSN : 2228-5482, For any comments and questions please contact us.